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go fuck yourself 

When someone tells you to go fuck yourself, they are encouraging you to shove your penis up your own asshole by bending it backwards. Or, if you're a female, to grab the nearest phallic object(s) and penetrate your orifices repeatedly. The connotation is that you'll probably enjoy it and will stop annoying everyone.
Broke Ass: "Hey man, can I have one of your beers out of the fridge?"

Working Man: "Go fuck yourself."
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Politely go fuck yourself 

When you want to say go fuck yourself while adding a bit of smartassness in.
A Random entitled bitch walks in back room in middle of dnd game REB- “Hey can y’all shut up”
Me- “Hey can you politely go fuck yourself”

hide and go fuck yourself

A derogatory term used when someone is annoying the shit out of you and you want them to leave.
Kris - "Hey dickweed"
Ash - "Kris...why dont you go and play a game of hide and go fuck yourself."
hide and go fuck yourself by HACH November 30, 2006

Go fuck yourself 

What I like to post on YouTube when I see those dumbass comments from those ungrateful moronic bots that post “I'm ˢᵘᵇˢᶜʳᶦᵇᶦⁿᵍ ᵗᵒ ᵉᵛᵉʳʸᵒⁿᵉ ʷʰᵒ ˢᵘᵇˢᶜʳᶦᵇᵉˢ ᵗᵒ ᵐᵉ ᵃⁿᵈ ˡᶦᵏᵉˢ ᵗʰᶦˢ ᶜᵒᵐᵐᵉⁿᵗ.......
Karen: You're fucking disgraceful and the world and everything centers around me and no one but me!
Me: Go fuck yourself, bitch.

Go fuck yourself 

A command uttered usually after one has said something infuriating or offensive to you.
Some people ask me why I curse so much. I respond to these people by asking them to go fuck themselves.

"Why don't you watch your mouth?"

"Why don't you go fuck yourself?"
Go fuck yourself by Disasterpiece January 23, 2008

Go Fuck Yourself with a cactus

Someone pisses you off, annoys you or is being a plain fucktard, Go Fuck yourself with a cactus
''I FUCKED YOUR MUM! ''Go fuck yourself with a cactus''

go fuck yourself 

Basically, means to just for the person to stop everything he/she is doing and find the nearest gun, point it under their chin and pull the trigger. That way they will no longer bother you and you can get some peace and quiet without their pure bullshit spewing from their mouths. If one continues you to harass you after you say this, you legally have the right to make them discover what your fist tastes like. They cannot sue you for any reason.
Latin origins of GO Fuck yourself:goeth fucketh yourselfus