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An older woman in their late 60s to mid 70s. She has been through it all: wars, depression, and the plague. She is coming around the block for another go at the young men. She bares flashy jewelry, diamonds, etc. She has a "If you got it, flaunt it" attitude.
So I skipped the cougar bar and went straight for the calico's, what a good time.
Calico by missmeeshiko September 21, 2009
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A:Hey who's that foxy, blonde haired, blue eyed girl?

B:Thats Calico!
Calico by DJ H July 4, 2009
When your crap has both light and dark colours in it's composition.
Hey Matt, I just took a crap and it was Calico!
Calico by bel97g March 31, 2009
A child whose mother had sex with many men, and as such, had no earthly fucking idea of who the father was during the pregnancy.
"Did you see that woman on Maury? She had 3 different guys on there and none of them were the father."

"Yeah, that kid's a Calico all the way."
Calico by UltimatePunchMan February 1, 2019
A cat that is a calico
That cat is a calico
Calico by NoiKoiBlizøLexxy April 28, 2022
Sick, not feeling well, under the weather
After double sessions during nationals training, I became Calico
Calico by pookie2224 February 1, 2023
"That calico is such a bizz-nitch"
Calico by SilverCurbsideProphet April 13, 2023