Tweak

(v) to tweak: a high resulting from methampetamines

He's the biggest druggie, he tweaks everyday.

by Cacoo June 26, 2003

Tweak

1. To adjust accordingly
2. To freak out

1. His guitar sounds like shit 'cause he's gotta tweak his amp.
2. When she heard me play my guitar she tweaked.

by Buzz Cola October 23, 2003

Tweak

Really jumpy, talks with his hands, basically the baddest mofo on a campus near you.

Look at tweak walkin outta math class.

by snaggatoof February 6, 2010

Tweak

To adjust or fine tune things, to personalise an object and make it better to suit one's liking

Holly was eager to tweak her sister's white canvas slip-ons with rainbow unicorns because she knew they were her sister's favourite mythical creatures.

by fln September 23, 2013

Tweak

A word most often used with the pretext "to pull a", this meaning of the word originated in Arroyo Grande, and refers to a resident who own a .50 cal handgun, and is the definintion of "badass"

Victor: Yo! Come watch me smoke this fool!
Tyler: Hey man! Calm down, you're about to pull a Tweak!

by k man gg May 7, 2009

Tweak

Thaaa coolest kid in south park

tweak is cool

by tweak July 18, 2003

Tweak

To stimulate a female's clitoris to the point of a micro-orgasm.

To the theme song tune of 'Kim Possible'. Call me beep me if you wanna tweak me.

by Kimfuckable May 3, 2019