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Hotopotamus 

A person, either male or female, who is sexy and attractive despite being seriously overweight.
Though he tipped the scales at 310, many girls considered Jason quite a Hotopotamus.
Hotopotamus by PMcClaran February 13, 2010

Twatopotamus 

A derogatory term for person who exhibit offensive, hateful, moronic or unbearably pretentious behavior to an exaggerated degree, that can be used on a man or a woman.

Derived from the derogatory American specific use of the word "twat" and the word "hippopotamus". The first word provides the implication of the unfavorable traits whereas the second just implies the extremeness of the individual's behavior as a metaphorical use of the animal's large size.

I will not state her name, but my own mother was the first person I ever heard use this term and she stated that the word was of her own creation. I claim that she is the originator of this term. I write this entry as shortly after she used the term on social media, Facebook memes appeared that made use of the term. Thus, this entry exists for all those that happen upon those memes who became curious for its definition and origin.
Shes being a twatopotamus!

Are we going to have a real conversation or are you going to keep being a twatopotamus?

Okay twatopotamus keep your hateful self away from me.
Twatopotamus by InfoBringer March 9, 2023

Twatopotamus 

A twatopatomus is an idiot that looks like a hippo.
Omg she’s so stupid! She even looks like a twatopotamus!
Twatopotamus by Twat__ December 24, 2019

Thotapotamus

A plus size gal who also happens to be a thot
Becky is such a thotapotamus , that's her 3rd guy today

thotapottamus 

A larger version of what people would define as thotiana. Could also be defined as big booty hoes, or larger versions of thotiana
There’s thotiana and then there’s thotapottamus.
thotapottamus by King Sully February 5, 2020

tittopotamus 

When a woman's breast are so gigantic they become weapons when she runs.
Damn that tittopotamus just rammed into me and I liked it!
tittopotamus by johnnybgoodOG December 29, 2022