S.O. 

Sexual Orifice

You know that song, Low S.O.

S.O. by slavetical June 2, 2003

S.O. 

Something other

I want to get a gift for her SO than the usual.

S.O. by poppi December 10, 2003

S.O. 

S.O. = Sexual otter

'Hey did you see the S.O. last night?' 'Yeah, man, that otter was realy sexy!'

S.O. by DuckStuff February 23, 2018

s.o. 

Spelled out. The full-text definition of an abbreviation.

The HSA (s.o., Humane Society of America) works to save animals.

s.o. by Pat the Kiwi June 9, 2022

S/O 

Short for “significant other”

One day I would love to go on a picnic date with my s/o

S/O by ChimCo September 14, 2020

S/O 

Shout outs to _______ . A commonly abbreviation used on Twitter.

S/O to my nigga @TRAGEDYKHADAFI7 it's good to have you home.

S/O by mikeyrocks September 2, 2010

S/o 

Short version of saying shout out

May:shay give me a S/o
Shay:ok boo

S/o by lilcece March 18, 2015