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Piss off 

There can be 4 meanings to the term piss off.
1. Yeah, totally. (Sarcasm)
2. Screw off, get lost.
3. To make someone mad/angry
4. A person whose job is to make people angry, a job done for pleasure.
1. "Yo, bro, I asked Megan out today. She said yes!"
"Piss off, you bitch"
2. "Who are you?"
"I'm James! You invited me to the jam!"
"Go piss off, I didn't invite you for shit."
3. "Hey, you shithead. You really pissed me off yesterday. It's time to pay."
4. "Greg, why are you being such a fucking piss off?"
Piss off by DefineModernShit November 4, 2014
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piss off 

To eliminate a hard-on (go limp) by peeing instead of ejaculation. This is disappointing to men, so they don't want to go to the bathroom and piss off their hard-on. Then then say they are pissed off, or angry about it.

It has become slang for making someone angry or when something or someone makes a person angry.

Today, women have picked up on this term also, using it as getting angry (but not about their hard-on going away).
I love my errection, but when I go pee it will piss off (original usage).
He is going to piss me off (modern).
piss off by Jimmie Boy May 23, 2006

Piss off 

follows by 'wanker'.

Just a couply banter between Louis Tomlinson and Harry Styles!
Anti 1: Hey,how can you even believe in larry,they hate each other!
Anti 2: Yeah,haven't you watched the iconic 'piss off-wanker' video?

le me: If you and your husband never fight,are you even sure you are in love???
Piss off by HazzaisLou's July 17, 2021

piss off 

Telling someone to get lost in rude way
A douche - looking guy at the party asked for my number and i told him to piss off.
piss off by burst of confidence January 2, 2018

Piss Off 

A race and timed event to see who can piss the longest after drinking a six pack of old milwakee while holding a glass of ice water thoughout the entire duration.
Gentlemen... let the Piss Off begin!
Piss Off by Koola User September 4, 2003

Piss off 

Any person who is constantly pissing you/others off or doing things to piss people off.
Wow that guy is such a piss off!

My ex is a piss off.
Piss off by Mz_Katie June 18, 2009