D.U.F.F.

Designated Ugly Fat Friend. If you know of a DUFF, You are a DUFF, or you've heard of a DUFF, you are in luck. Because I hate to break it to you but you are a DUFF. You don't have to be fat or ugly to be a DUFF. DUFF is just a catch for a person who doesn't fit in. If you ever felt left out, excluded, or just different it means you were a DUFF and potentially are one now. But don't worry. Being a DUFF is a good thing. It means you are an original person. SO pump your fist in the air if you're a DUFF!
by ThtYllwBch June 07, 2015
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D.U.F.F.

Damn that bitch is a D.U.F.F. Damn your sister's hot, and who's the DUFF?
by Pwat April 19, 2006
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Duff (D.U.F.F.)

abv. for Designated Ugly Fat Friend; Term men use to describe a fatter, less attractive friend, a woman brings with her to a party or social gathering to make herself look better by comparison. In some cases the more attractive woman will not "put out" for any male, unless one of his friends "takes one for the team" and "hits" the Duff.
C'mon take one for the team and hit that Duff (D.U.F.F.), I'll buy you lunch tomorrow!
by Dr. Slappy McGee III Esq. March 07, 2006
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D.U.F.F

Standsfor:Designated Ugly Fat Friend
The Duff is the girl or boy in the friend group who is always doing there friends homework and does not have a great sense of style, probably wears alot of baggy jeans and is mostly feeling left out,every friend group has a DUFF and the Duff is not really fat just not as cute or cool as the rest of the cliqe and the DUFF has messy hair maybe short
Guy:OMG look it's them
Other guy : wait who's she
Guy: oh she's KENDALL /THE D.U.F.F
by Cuteuwu97 December 22, 2019
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