This expression translates directly to, 'the immaculate octopus mary magdalen' and is used to express awe in a situation of disbelief and utter shock.

Only those of profound knowledge are able to attain such vocabulary of mass intellect. It is said to have been passed down from generations.
e.g. Kenneth: kont taf li il-bajd ta Gandhi ghandhom riha ta laham nej? (did you know that Gandhi's ball sack reeks of raw meat?)

Maurice: l-immakulata qarnita marija madonna, waqqajtli tlett sufiet minn imniehri! (he immaculate octopus mary magdalen, i have shed three nose hairs!)
by ommok69 January 16, 2023
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Madonna Zappatrice

A common 'bestemmia' used mainly by idiots who's name is 99% of the time Liam. Madonna Zappatrice is used by Liam to trigger Sebastiano's teakwondo skills that may be lethal.
Liam: "Madonna zappatrice di cappelle nel culo"
Sebastiano: "Liam non si dicono le bestemmie porco dio"
Liam: "Adesso scappo se no mi uccidi con il tuo taekwondo del cazzo"
by L'inter fa schifo October 17, 2023
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madonna cogliona

it's an anal exclamation for angry people that smoked crack
madonna cogliona,passami subito quella pipa!
dio coglione di merda,rivestiti madonna cogliona!
by CRACKMOLESTO March 01, 2019
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Madonna university, Nigeria

A type of punishment given to people for sins of their childhoods.

A way parents escape their least loved children.
Even sec man has more rights than the students in Madonna university, Nigeria.
by Acetaminophena October 21, 2023
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Madonna

A strong independent woman. She is very smart and technical, once you become friends with her you and her will always be friends. Madonna is a very trusting woman, you can always talk to her, you can always laugh with her. Madonna is one of the funniest people you will ever meet. She loves going out for adventures and seeing the world. She is also very down to earth most the time! But be careful if you get in her/her friends bad side, she will go full beast mode
Guy: who’s that?
Girl: That’s Madonna!
Guy: ohhhhh yeah she’s cool!

Girl: she sure is.
by Katilyn hadders January 20, 2021
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Madonna

Oh Madonna! The Pope just imploded!
by what kinda name is soap December 23, 2022
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