Duff

D.u.f.f- Dumb Ugly Fat Fuck, only used with girls but can be used with guys if necessary.

That girl at that lunch table eating jello is a fucking duff

by Kevin Derr May 4, 2007

Duff

Designated Unpopular Fat Friend. A fat person,usually a female who is obsessed with a country boy,his friends,his momma,sister,truck and dog.

Girl: Where did all my ice cream go?
Boy: The duff must have ate it.

by brotherman94 February 8, 2012

Duff

The cannabis material that is left after vaporization (which it is still good for cooking).

I made awesome brownies with the duff from last weeks party!

by CaraBeantown January 5, 2014

Duff

Dumb Ulgy Fat Friend. The one friend that people only talk to to find out info on their hot friends

I want to find more stuff out about Nikki. I'm going to ask her Duff

by thatonegirl3000 March 8, 2015

Duff

to spill something on your clothes.

I duffed my coffee this morning during the commute.

by Argh Dammit September 25, 2005

Duff

1.A incognito way to compliment a nice behind without being heard or looked at by the selective the female target.the term started in NJ in the summer of 2007 and is now being used by college students,frat brothers and perverts up and down the east coast!

2.Nice Big round mound of butt that defies the laws of physics.

1.Jimmy have you seen "Billy Duff"? (while pointing out a target)
2.I was strolling down the beach earlier and saw a "Duff".
3. "Duff" to the right!
4. That's quite a large "duff".

by Joemy mckenzanela November 19, 2010

Duff

designated ugly fat friend

"Your their Duff, they are prettier than you"

by heyo2 May 30, 2015