A disease caught by picking up too many cards in UNO when playing by the rule "Pick up until you can put down" when needing a card.
Michael:"I Change colour to Blue"
Nick: "Darn."
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
John: "Oh damn."
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Ash: Bro he's got Pick-up-till-put-down Syndrome!
Nick: (picks up card)
Nick: Finall-wait nevermind.
Nick: "Darn."
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
John: "Oh damn."
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Nick: (picks up card)
Ash: Bro he's got Pick-up-till-put-down Syndrome!
Nick: (picks up card)
Nick: Finall-wait nevermind.
by NinjaSlayer_936 January 1, 2021

pick/me are neo-prouns meaning, you want to be fucked in the ass and have degrading and piss kink.and you want to be raped.
by don’tyoucryovernospilledmilk June 18, 2021

An actor who gets in a play with a lot of assistance from actor friends and then ditches said actor friends in the play THEY ALL AUDITIONED FOR, then proceeds to suck up to other, 'superior' actors, director, stage manager, etc.. Typically acts different around friends than around superiors, much like the pick me girl.
by Cephalopedia December 1, 2023

"Pick-me girl" is a term used by jealous femcels to insult a popular, feminine girl who is aware that the modern, strong, independent feminist mindset only drives men away from those types of women—the same ones who insult her with that term. So, they resorted to inventing it as an 'insult' because she chose not to subscribe to their 'I don't need no man/I'm a strong independent woman' femcel trash mentality.
A pathetic femcel might say something like: "She thinks acting all sweet and submissive will get her attention from the guys, but it just makes her look like a pick-me girl. So pathetic."
by The only king is God February 16, 2025

by Michael December 7, 2021

a girl or boy who acts like a big softie and sweetheart until you meet there real personality (mean)
me: DUDE MCKENZIE IS SUCH A PICK ME GIRL
syrenity: IKR SHE JUST TURNED HER BACK ON SAGA EMMA AND CLAIRE
me: she’s the biggest pick me girl I know
syrenity: same here girl
syrenity: IKR SHE JUST TURNED HER BACK ON SAGA EMMA AND CLAIRE
me: she’s the biggest pick me girl I know
syrenity: same here girl
by hilary :))) January 29, 2022

by mcnazty May 29, 2023
