Chronic Mediocrity Syndrome 

A sad and mildly debilitating condition in which the sufferer will never be exceptional in a chosen discipline or field of study, no matter how hard they work. While incurable, it can often be treated/maintained with a reality check.

I'm sorry Mrs. Smith. You might as well stop your son's violin lessons. He will never be a virtuoso. He has chronic mediocrity syndrome.

Chronic Mediocrity Syndrome by Blursaw March 1, 2010

Toy Story Syndrome 

An inability to throw out or sell old toys and/or objects from your childhood as a result of seeing toy story (1, 2 or 3), and thus having an overly sentimental view upon these objects and imbuing them with anthropomorphic qualities. Ultimately a dangerous syndrome when combined with those partial to 'Hoarding'.

John: Wow Dave, you really do have a lot of junk lying around your house, didn't you have a garage sale recently?

Dave: Yeah, i did, but when i looked at those little G. I. Joes i used to play around with i remembered all the personalities i gave them, and all the games we used to play...

John: Yes, but now you are 34 years old and do not play with them anymore, and they sit gathering dust in an increasingly over packed room where something useful could be

Dave: I guess so, i suppose i might be coming down with Toy Story Syndrome

Toy Story Syndrome by Natsnud January 2, 2012

resting bitchface syndrome 

Or R.B.S. is defined as the thousand yard stare and overall uninterested, angry looking gaze that falls upon some women. Usually first diagnosed around age 20 it can both be genetic or influenced by ones environment to where the afflicted appears "bitchy" in absence of a smile.

Barb has a bad case of Resting Bitchface Syndrome

resting bitchface syndrome by Nolin Chitwood February 15, 2015

Fallout 4 Syndrome 

A drive to collect items of importance you find in Fallout 4 in real life.
I.E.: Globes for screws, Duct Tape for adhesive, aluminum cans for aluminum and/or any bottlecaps.

Aw man I played Fallout 4 all weekend! Yesterday I saw a globe and something in me told me to go grab it so I could a screw from it, the same thing happened with a roll of duct tape just a few hours later! I think I got Fallout 4 Syndrome...

Fallout 4 Syndrome by Psymon The Cat March 9, 2016

Solar Penile Syndrome

In rare and unknown circumstances, the dick and balls disconnect from the body and fly into the sun, being known by medical professionals as Solar Penile Syndrome (SPS).

Harry: Holy shit your balls flew away!
Tony: I have Solar Penile Syndrome

Solar Penile Syndrome by wide idiot June 21, 2020

Among Us Syndrome 

What happens when you are playing among us
And then lose
Symptoms include:
Trust issues-
Anger-
Being an asshole-
Extreme use of the word sus-
Mentally scarring you for life-

Black: Hey I have "Among us syndrome"
Pink: What does that mean?
Black: It means
"Five minutes later"
Announcer: Defeat
Black: YOU STUPID PEICE OF SHIT I KNEW IT WAS CYAN I KNEW IT
Pink: Calm down dude
Black: YOU'RE ACTING SO SUS RIGHT NOW

Among Us Syndrome by N the impostor September 20, 2020

Will Syndrome 

This mild syndrome refers to the actions hard-core gamers do when the lose a video game. The phrase "will syndrome" was pawned after a "hardcore" gamer started throwing his controller at friends' faces and/or body when they defeated him in a video game. Today, when any person will flip out on a friend or family member for a stupid or unnecessary reason, they are said to have Will Syndrome (WS). Just before and usually after a person has an outbreak of WS, unnecessary comments involving the words "Jew" "Fuck" "Fag" and "Nigger" will occur. Most of these comments being said from a lack of brain power (caused by a combination of weed and too much video games) to think of any sort of remotely intelligent insult. Today Will Syndrome is a commonly overlooked problem, but can be very serious and may cause serious physical and emotional damage.

"Dude! Why did you hit me in the face with that controller? Its only a f**king game! You need to get your Will Syndrome checked out by a doctor"

Will Syndrome by Flabbergasted Gamer November 1, 2007