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smoke yourself a spare chromosome

To smoke weed until you're retarded, as Down's Syndrome is cause by the presence of an extra chromosome.
Chich : We finished a quarter ounce between us last night, man. I think I'm still kinda faced.

Chung : Shit son, you don't watch out you'll smoke yourself a spare chromosome.
by Parhelion February 22, 2009
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Smarties Smoke

When someone (typically teens 13-17) crush smarties and puff the sugary powder out of their mouth imitating cigarette smoke
hey want to go for a smarties smoke?

psh duh! it will be totally trippy
by discoveringwithabeat August 20, 2009
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Related Words
smode smoded smodem smodeu smoke smoked smoke screen smoe smoked out smod

smoke

To kill someone or to eliminate someone

To win a race
by Lanna Cabana July 19, 2016
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smoke a j

means were about to go smoke a good ol joint ie marijuana joint
"yo g we gunna smoke a j"
by Ben. s Hall February 5, 2008
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smoke hand

One who masturbates so frequently or so furiously that one would expect to see his hand smoking afterwards.
Have you seen Adam today? No, we got high speed internet last week and he's been in his room ever since. Man, what a smoke hand.
by 3rd from the left May 11, 2010
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Smokehags

Unattractive, mouth-breathing, lazy females who take cigarette breaks every 30-45 minutes. Commonly found populating trailers on construction sites.
Oh look James, the smokehags are back in the smoke pit.
by Stinky Chief July 27, 2012
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smoke a butt

Yo Chris you wanna smoke a butt?
by SchoolboyQ December 28, 2013
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