To smoke weed until you're retarded, as Down's Syndrome is cause by the presence of an extra chromosome.
Chich : We finished a quarter ounce between us last night, man. I think I'm still kinda faced.
Chung : Shit son, you don't watch out you'll smoke yourself a spare chromosome.
Chung : Shit son, you don't watch out you'll smoke yourself a spare chromosome.
by Parhelion February 22, 2009
Get the smoke yourself a spare chromosome mug.When someone (typically teens 13-17) crush smarties and puff the sugary powder out of their mouth imitating cigarette smoke
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Imma (smoke)that bitch!
by Lanna Cabana July 19, 2016
Get the smoke mug.by Ben. s Hall February 5, 2008
Get the smoke a j mug.One who masturbates so frequently or so furiously that one would expect to see his hand smoking afterwards.
Have you seen Adam today? No, we got high speed internet last week and he's been in his room ever since. Man, what a smoke hand.
by 3rd from the left May 11, 2010
Get the smoke hand mug.Unattractive, mouth-breathing, lazy females who take cigarette breaks every 30-45 minutes. Commonly found populating trailers on construction sites.
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