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Super Tweaker 

One who Does Crystal Meth and mows the lawn at 2 am while it was raining out in nothing but a wife beater and flip flops.
"Did you see the new neighbors?"

"Yeah they look like a wild pack of Super Tweakers"
Super Tweaker by Immortalwombat7 December 30, 2014
A person who does Crystal Meth. They talk very fast all the time. You're lucky to get a word in with a serious tweaker. They do obsessive projects ranging from, taking a TV set apart, to cleaning a tile floor with a tooth brush. Not finishing anything is common. The thing about meth is that some people have done so much, that even when they quit, they are so damaged that they retain all the characteristics of a tweaker. Ruined for life.
That dude is such a tweaker, he won't stop talking!
tweaker by Roadie Overthegate March 11, 2007

tweaker slut 

A girl that likes methamphetamines and sex so much that she spends the majority of her time in front of the mirror applying layer after layer of makeup so she will look good for sex.
My tweaker slut roomate was in the bathroom for eight hours yesterday putting on makeup.
tweaker slut by Jamie Pheloney April 9, 2005
Most commonly known as a speed/meth addict.
Less commonly known as: a female stoner.
1) "Look at Tim smokin that shit in the corner...what a tweaker."
2) "Yeah, Dori's such a tweaker!"
tweaker by Yramesor! April 14, 2004
Some one who does crystal aka tweak and has been up for days showing signs by talkng alot pacing around and fidgiting
"Damn Pavells A Tweaker now"
Tweaker by Lisa April 9, 2004

Tweaker Lag 

The state of sleep deprivation caused by the use of amphetamines or any type of stimulant for prolonged periods of time.

Not to be confused with jet lag.

This lag often transcends into psychotic episodes which may include cleaning things over and over again or taking something apart and rebuilding it but never quite getting it right.
Dude #1

"Look at Chris, he hasn't stopped working on that car for weeks"

Dude #2

"Hes got Tweaker Lag"
Tweaker Lag by essentrabalance August 27, 2009