Issa

Short for "it's a" popularized by 21 Savage. In a word ISSA the first 2 letters "IS" literally look like 21 if it was mirrorized.
by Issacool July 08, 2018
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issa

ebonicit’s a”
Congratulations, issa Boy! Congratulations, issa Girl!
by Champagne Dylan January 14, 2022
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issa

it’s a” but yk put together.
by dtxx.david March 31, 2021
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Issa

by Iyk October 29, 2021
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hakim issa

you are so hakim issa
by hakim bb girl November 16, 2022
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Issa no 4 me

When you reject something--commonly said by a female or someone of female character-- because you find something offensively ugly, you just want to respond w/ a sassy no, or something offensive in general.
Also sometimes sided with a teacher eating gesture-- curling your pointer finger in front of your mouth while giving the look-- to add exaggeration to the rejection of an irk
____: bro Ryuk from Death Note is like so hot. I mean the eyes, the hair, the bod--

Me: issa no 4 me. He is not attractive sry not sry.
by Anonymous#518819738 September 04, 2022
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~issa mood sis~

Something you say to your friends over relatable topics.
Most of the topics are over guys, exes, or just stupid things in general.
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Credits to creators of this definition... Alexandra Mackenzie and Hannah
Feel free to add us, the crackheads on Snapchat
-Alexandra (Alley) @alley_t03
-Mackenzie @mackenzie4125
-Hannah @hannahpilgrim16
A: He's such a confused boy.
M: Confused is an understatement.
A: ~issa mood sis~
by crackheadlife101 November 22, 2019
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