hormone blockers

Hormone blockers, also known in some contexts as puberty blockers, are used by transsexuals to block various sex hormones. For instance spironolactone, a diuretic, is often prescribed to male-to-female transgender persons to block androgens or male hormones.

A hormone replacement therapy (HRT) regimen usually consists of at least two prescription drugs: hormone blockers to block the original hormones, plus a new, replacement hormone in the desired gender. For instance, an M2F transgender patient may be given spironolactone to block male hormones (androgens, testosterone) plus a female hormone such as estrogen (Premarin, a drug made from pregnant mares' urine, for example).

Once the original genitals (testicles or ovaries) are removed, the blocker is discontinued, leaving just the hormone replacement.

by bitchuck August 31, 2024

Hormone hangover

Those incredibly shitty and painful mornings when you wake up and are on your period. Your have cramps, your lower back hurts, you're slightly nauseous from the pain, you feel like you have a fever, sometimes a headache and everything just hurts.

I had to text my roomate to get my midol and hot water bottle cuz i have a wicked hormone hangover and I can't even fucking get up.

by Microwaves July 31, 2024

Hormonal Technologies

The tools and devices that enable the monitoring, analysis, and manipulation of hormonal states. This includes at-home saliva test kits, wearable sweat sensors that track cortisol, implantable hormone pumps, and AI-driven apps that correlate mood/energy logs with hormonal cycles. These technologies turn the abstract science of hormones into actionable, personalized data, empowering (or sometimes obsessing) individuals to become the mechanics of their own endocrine machinery.

*Example: "Her smartwatch now includes hormonal technology—a micro-needle patch that analyzes interstitial fluid for estrogen and progesterone trends. Her phone buzzes: 'Your luteal phase spike suggests high productivity window for the next 48 hours. Schedule demanding tasks now. Also, you might crave chocolate.'" Hormonal Technologies

by Abzugal January 30, 2026

Hormonal Engineering

The deliberate design of interventions to modulate, mimic, or suppress hormonal pathways for desired outcomes. This ranges from creating synthetic hormones and receptor blockers in pharmaceuticals to designing lifestyle protocols (light exposure, meal timing, exercise regimens) that hack the endocrine system. Advanced concepts include gene therapies to recalibrate hormonal set points or implantable bio-sensors that release hormones in a closed-loop feedback system.

Example: "The biohacker was into hormonal engineering. He used a continuous glucose monitor, blue-light filters, and precise weight-training timing to keep his insulin sensitivity high and his cortisol curve flat. He wasn't just living; he was conducting a symphony of chemical messengers with his daily routine."

by Abzugal January 30, 2026

Hormonal Sciences

The interdisciplinary study of hormones, encompassing endocrinology, biochemistry, neurobiology, and behavioral science. It explores how these potent molecules regulate everything from mood and metabolism to sleep and social bonding. This field moves beyond glands and receptors to understand hormones as the body's information network, integrating environmental cues (like light, stress, or nutrition) with genetic blueprints to orchestrate complex physiological and psychological states.

Example: "Her PhD in Hormonal Sciences wasn't just about glands; she studied how oxytocin scripts social trust in the brain, how circadian hormones dictate the best time for chemotherapy, and why a cortisol spike can make you both sharp and anxious before a big meeting. She called hormones 'the chemical sentences the body uses to tell itself stories.'"

by Abzugal January 30, 2026

Hormonal Thermodynamics

The study of the endocrine system through the lens of energy conversion, entropy, and non-equilibrium processes. It examines hormones as chemical messengers that orchestrate the body's energy budget—allocating calories to growth, stress, reproduction, or rest. This field asks questions like: What is the thermodynamic efficiency of a stress response? How does the entropy of a cellular signaling cascade affect metabolic rate? It views hormonal balance not just as chemistry, but as a dynamic, heat-producing management system for the body's limited energy reserves, where hormonal "decisions" optimize survival against thermodynamic constraints.

Example: "My crash diet failed because of hormonal thermodynamics. My leptin levels plummeted, signaling an energy crisis. My body's internal regulator slammed the brakes on my metabolism (reducing heat output) and cranked up cortisol to scavenge energy from muscle—prioritizing survival over my beach body in a brutal, energy-efficient way."

by Abzugal January 30, 2026