A slang term for the very serious medical condition duphershypertrophy whereby the sufferer acquires over time excessive fatty tissues to the nasal region, giving the patient the not unpleasant features of a gnomish looking fellow; rosy cheeks from the strain of holding one's nose up all day, at times somewhat gormless facial expressions (which can be attributed to the drag-factor but more often can lead an innocent bystander unaware of the condition to conclude that the sufferer is possibly some sort of simpleton) and of course the ever-expanding, bulbous nose which grows and grows like in that fable about the enormous turnip...
Prognosis: Not good; rhinoplasty recommended.
Prognosis: Not good; rhinoplasty recommended.
What are you doing resting your nose on that snooker cue? Have you got Duffers' Syndrome or something?
by Mouldy123 April 3, 2011
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Get the damien duff mug.A sandwich served to you while in jail, the drunk tank and/or prison. It is a bologna sandwich made of expired lunch meat, stale cheese and moldy bread. May come with other condiments, but don't get your hopes up, its jail food!
by Boomhowser September 9, 2009
Get the Duffy Burger mug.A term that was popular in the early 2000's and is an acronym for "designated ugly fat friend." In modern day, this term is only used by douches who can't keep up with current slang, and by stupid ass middle schoolers who think they are the shit because of the 2015 movie of the same title that attempted to resurrect the term and make it "cool."
Stupid Person 1: Why is that ugly bitch hanging out with those hot girls?
Stupid Person 2: She must be the DUFF.
Stupid Person 2: She must be the DUFF.
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