tweak

To be on the come down of drugs such as methamphetamine, in which one begins to hallucinate or "bug out"

I've been up for 2 days an now I'm tweaking.

by bkz_allstar March 23, 2011

Tweak

to lightly caress with the thumb and forefinger

"Tweak those nipples and spank that ass!"

by Knowerofallthings April 26, 2006

Tweaking

To dance in a particular way referencing Bobbie Shmurda's song "hot nigga".

She tweaking hoe!

by Bholmes_xo November 26, 2014

Tweak

Someone who overly acts weird, reacts in a weird way, or acts unnormal and squarish.

When a teen acts too excited in class and starts tweaking out.

by magsoldier15 January 21, 2011

Tweaking

another word for banging

We were tweaking last night and the rubber broke.

by Brownhole24 October 8, 2010

tweak

adjust a small amount for improvement as in a race car or computer settings

I entered my computer bios and tweaked the memory settings.

My car is oversteering, I will tweak my camber settings.

by earl February 13, 2005

tweak

(1) to act like a spaz (see spaz) (2)to be incredibly hyperactive to the point that people believe you to either be mentally insane or hopped up on something (while not under the influence of drugs)

Did you see how Doug was tweakin' the other day?

by JK April 3, 2005