In the duff

When you are horny as fuck

Yo bro are you in the duff right now?

by c0pen September 8, 2020

Duff

A friend nobody really wants to be around but is tolerated and kept around for the purpose of buying alcohol

an example: duff as in a person around just for alcohol

by 203.goon July 25, 2020

duff

adjective describing something lame, or stupid; opposite of kuff

Damn that party was soo duff, way too many dudes in there.

by kufflos January 15, 2009

duff

English word for semen.

Last night I shot my duff right in her eye.

by The Strut September 29, 2004

Duff

Verb; meaning to punch or hit.

"Shut up right now, or I'll duff you!"

by AndreaMK December 3, 2006

Duff

Designated ugly fat friend

Duff - a less attractive person who has really hot friends and is an easy target to talk too while out at a party/bar too hook them up with the hot friends

by Eloks July 29, 2015

Duff

UK - to be pregnant

She's up the duff

by Sophie96 April 11, 2015