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Derogatory term originating in New England to refer to somebody from Massachusetts. Most commonly used while driving.
Dammit! That masshole just cut me off!

Sorry I’m late for work, all the masshole leaf peepers caused a traffic jam on Route 101.
Masshole by mayanaze November 11, 2021
Sean R. 1A-1
Mike: Dude, have you seen Sean from Worldwide? That guy is a total masshole.
John: Dude for real, he's almost as bad as Polecat.
masshole by WWRP< May 18, 2022
Total cunt that tried to run you off the road in lowell, MA they need to be hunted down and beaten
I hope that masshole gets cancer.
Do you wanna do it in my bussy/mussy or my masshole?
masshole by Saucy Osbourne July 25, 2022
In other words pussy, they are the people who act like there on there period in the road , 95% of the time they have never been in a fight but will act tough behind the wheel untill someone steps out the car and they speed off scared .
The masshole was beeping at the old lady for no reason untill her son stepped out the car and they sped off scared
Masshole by Jacks 77 February 20, 2026

masshole merge 

The method used by drivers from Massachusetts to merge in a construction zone - driving as far in the lane that is ending and then forcing traffic to stop in the continuing lane as they force you to hit them or let them in.
That guy tried the masshole merge and got himself an ass full of Peterbuilt