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Winnie the Pooh's way of saying Motherfucking Shit.
Piglet: Pooh, you're out of honey!
Pooh: oh bother.
oh bother by Dildos. November 26, 2013
Piglet: Oh no! Tigger's bounced all over the vegetable garden and ruined the carrots!

Winnie the Pooh: Oh bother!
oh bother by noorbert August 10, 2018
Winnie the Pooh's equivalent of "Oh fuck"
Friend: bruh the last guy is a legit skull trooper with 24 kills
Me: oh bother
Oh bother by alee2006 August 9, 2018

Oh Brother 

Winnie the Poohs equivalent to "Mother Fucking Shit"
Oh Brother, we're out of Honey.
Oh Brother by tastybitch69 November 12, 2012

oh brother 

not happy ( something is wrong )
oh brother my taxes are up again no wineo white heads!!
oh brother by itichie_nocanpo August 10, 2006

Oh Brother, He's Made of Wood. 

A phrase used to articulate feelings of immense loathing of someone that is known for unintelligent or troublesome actions. The phrase being used when a particular action comes into play. Usually followed by a facepalm.

Origin: First used in season 4 of "Futurama", episode 68 - "Obsoletely Fabulous". Bender, because of his new found hatred for advanced technology, has had a downgrade, making him a wooden, steam-powered robot. Bender enters the scene and Leela immediately exclaims "Oh brother, he's made of wood."
Leroy: "Is that Clyde over there?"

Jeff: "Dammit, I think so. What's he up to this time?"

Clyde: "Hey Jeff! Check it out! I found this guy down at the hospital on 42nd street! He seems pretty cool! Check out his cool bracelet!"

Leroy: "Isn't that 'hospital' a personal care home for the mentally ill?"

Jeff: "Oh brother, he's made of wood."