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To be insane, crazy, or senseless.

If you discuss something that is taboo, then you might be meshuga.

If a person acts in a way that senseless, he or she might be a meshuga.

Yiddish roots
The hysterical executive responded, "are you meshuga? Ask me about anything else... but please, not about THAT"

Mendel: Come on Heschel, schlepp on over to the butcher!
Heschel: Mendel, are you meshuga? that place isnt kosher!
Ruva: It doesnt matter, neither of you two are straight up jew.
meshuga by g-diggity April 15, 2008
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a crazy person , a person who does crazy things.
woa! did you see that guy jump on to the subway tracks! what a meshuga!
meshuga by aarojac June 22, 2004

mesugaki 

(n., Japanese メスガキ, probably from 雌 (mesu) "female" + ガキ (gaki) "brat")

Usually derogatory. A mesugaki is a kusogaki who is a brash, devilish little girl (often times a loli) who teases adult men, typically in a vulgar manner, sometimes overly promiscuously.

Pixiv dictionary attests that the term has been used since at least 1996, in Kindaichi Shonen no Jikenbo (金田一少年の事件簿).

The male counterpart is "osugaki", but this term is extremely rarely used.
Eh?! Seriously? You're 40 years old and still reading a high-school doujin? Are you a pervert? Lolicon? No wonder no one will date you with a face as creepy as yours~ wwwww

(Typical mesugaki dialogue.)
mesugaki by AsacocoEnjoyer June 3, 2021

Meshugga 

A Yiddish word for crazy or crazy person. Many times it can be used as a term of endearment by Jewish Grandmothers or Babushkas.
My grandson is such a meshugga but he is so adorable... and needs to eat more!
Meshugga by waywardcello May 24, 2009

meshugaas 

Yiddish slang. Madness, Craziness, stupidity.
The stockmarket is meshugaas!
meshugaas by C.Lyons December 2, 2004
n.

1. A metal band from Sweden whose music features many dizzingly complex polyrhythms and hemiolas characteristic of free jazz and African drumming.

2. A metal group whose rhythmic concepts tend to go right over the heads of most metal fans, leading them to pigeonhole the band with such descriptions as "toughest band I've ever heard," thus raping them of the credibility they deserve.

adj.

1. Yiddish for "crazy."
Meshuggah is meshuggah!
meshuggah by Sommy July 9, 2004
progressive metal band from Sweden.

features of their music are;

-polymeters
-polyrhythms
-free-form solos similar to modern jazz
-extremely brutal sound, almost binary in dynamic nature.
"meshuggah are innovating a whole new genre of music that will be copied for many years"
meshuggah by cyrus beaumont August 18, 2004