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Someone who codes graphical user interfaces (GUI).
-Who is the person doing the new interfaces?
-Michou is the GUIne.
GUIne by NoWoL May 16, 2010
Italiano Or Italiana, Basicaly The Best looking that Italian Americans Have to offer. I.E. Fucking Hot Italians, May or may not have an intelectual Base.

But God They Are So Hot!
Male/Italiano) Seth Cormier
Female/Italiana) Angela Rubino
Guine by TAP February 16, 2004
derived from the word Penguin: an aquatic black and white bird with a bad temper and dislike for people.
Alex, Don't be such a guine.
Grace, stop your guining.
Jordan likes to guine.
Guine by Fancy Pants Mcfee February 12, 2014
when you lose the touch of reality and then proceed to tweak the fuck out
Person 1: "aye you heard about bro?"
Person 2: "last time i checked he was going guine"
guine by guineout September 21, 2023

Guine Stache

A mustache you gain from the foamy goodness of a guinness beer, or Something a guinea pig might have
Look at that guys guine stache, he must love that beer!

Look at that cute guinea pig his stache makes him look so much cooler!
Guine Stache by Zombie25 June 26, 2010

guinea pig shots 

The act of holding one's beveridge above one's head and against a wall. Then tilting the drink back and proceeding to suckle the liquid from the container as a guinea pig would water from its water bottle.
I blew so many chunks last night from all the guinea pig shots we were taking; it was a wild night.

"Dude! Guinea pig this Burnett's with me! Go Deacs!!!!"