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1. To be worried or scared about something, frequently used to describe a drug-induced state of paranoia.

2. To vomit.

Origin: Great Grimsby. Possibly originally evolved from the word 'defecate', via 'shitting it'.
1. 'I'm deffing', 'She's deffin'-out', 'I deffed-out', 'Deff-out'

2. 'I just deffed'. 'He's deffin''.
Deffing by spacecaked March 31, 2011
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1.)
To perform any action, or partake in any activity you would not do unless at a high level of intoxication, and usually regret the action afterwards.
Kev: Did you what happened at the last FFF?

Dave: No, what?

Kev: Duffin got drunk and claimed he was an ominpotient 'sort of thing'

Dave: I know dude, I filmed it!
duffin by David Read January 28, 2008
Related Words

Doing a duffin

To make unwelcome or uninvited conversation or sexual advances to a member of the opposite sex.
He is doing doing a duffin again. Mary does not look happy .
Doing a duffin by Wrd112 May 28, 2018
When a group of knob heads gather to wreck their cars by spinning around in circles, usually done by joy riders from west belfast and little boys who think twin (tin) cams and old beemers as old as the hills are cool
diffing - does she go round mister..
Diffing by diffin is for losers August 19, 2008
Word of the Day on March 24, 2019

Duffin Top 

When a man/womans' muffin top, has a muffin top. A more detailed version would be a double muffin top. but is mostly shortened to Duffin Top. Normally happens when the person tries to stick they're fat in theyre jeans, but still bulges somehow.
Guy 1: Dude did you see that one chick!?
Guy 2: ugh... total duffin top.
Duffin Top by 97k November 20, 2011

Duffinator

A girl named Niamh Duffy who has large bosoms and is retarted. A Duffinator usually displays symptoms of ADHD, autism and schizophrenia.
A: Ew have you seen the new girl, she’s so dumb!
B: Yeah she’s such a Duffinator
Duffinator by t2lavish October 28, 2020
To Duffin, is to either
1)DR/Disrespect some1
2) Make an ass of urself
Guy 1: you just duffin'd Sean
Guy 2: you just made a Duffin of urself

Duffin by seaniebabi March 26, 2008