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Pinky and the Brain 

Pinky and the Brain, a show that was first aired as a small sketch with the Animaniacs, are two white lab mice.

Brain, voiced by Maurice LaMarche, was the genius, coming up with inpossible schemes to take over the world.

Pinky, voiced by Rob Paulsen, was the comical side kick with his phrase, "NARF!"

The show itself was aired from 1995-1998, and ran for 65 episodes. PatB won an Emmy for animation in 1996.
Pinky: Gee Brain, What do you want to do tonight?

Brain: Same thing we do every night Pinky: Try to take over the world!

Pinky and the Brain is a classic, anyone would agree.
Pinky and the Brain by Shenkisshi August 21, 2006

herpes of the brain 

A condition associated with a stupid person. A person who cant think for themself. A person with nothing upstairs. Someone who has HERPES of the brain instead of the body. It impairs their thinking and makes them become brainwashed easily.
Mikey Rehmeer has herpes of the brain.
herpes of the brain by sjeeee January 10, 2008

sand on the brain 

A description used for someone who has said or done an incredibly stupid thing, that it is attributed to them having sand on their brain.
Friend 1: Hey dude, Friend 3 still thinks we only use 10% of our brain.
Friend 2: He's got some sand on the brain.

Easy On The Brain 

An expression of respect for somebody who is smart.
“She’s not just attractive, she’s also easy on the brain
Easy On The Brain by Uk.1988 August 27, 2020

Easy on the brain 

To tell someone to take it easy or slow down. Particularly relating to their head /brain or relating to someone who is overdoing it with their studies /homework.