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mainliner 

One who injects drugs into their bloodstream with a needle.
Ohmygod, he's not only a mainliner, he reuses his works! Do not exchange any bodily fluids with him no matter what.
mainliner by mjrn April 11, 2006

Mainland High School

Everything is not as it seems. This Daytona Beach school has a surprisingly nice campus that was wrecked in moments by the below average students. Every student from Mainland agrees that they are the best school around; however, no one else seems to agree. The athletics actually are not top ranked, but the students will say otherwise. The school is most notoriously known for being the most ghetto school in the county (being challenged only by Pineridge High School). The school is also known for the fact that the local celebrity Sydney Beiber. Most civilians would agree that Mainland is NOT the school that they would prefer to attend.
Mainland High School student: Ya, we are basically perfect.

Everyone else: Ok but no. Stop.
Mainland High School by Ooo killem October 30, 2013

The Mainland 

The Mainland by Faxx January 5, 2008

Mainland High School

Mainland High School is a synonym for a living hell. Notably the most ghetto high school in Volusia County, Mainland High School is known for fights, hot cheeto girls in every corner, and drugs on campus. There is a 99.9% chance that you will be threatened to be beaten up by someone for no valid reason at least once while you attend this school, if that doesn’t happen to you, then there is a 99.9% chance you will be emotionally damaged far before you leave Mainland. The majority of people at Mainland High School are not even passing their classes. Oh, I almost forgot to mention that we thought there was a shooter on campus once because a few people let off fireworks. This school has a bad reputation for many reasons, and if you’re zoned for this school I highly recommend going on a variance for a different school.
“What high school are you going to?”
“Mainland High School, what about you?”
“Oh.. I’m going to Seabreeze. I heard Mainland’s a really bad school.”

the mainland 

Place where Hawaiians go for a decent education and real experiences before settling down back on the rock.

also known as Mainland
Those haole's from the mainland drove me back home.
the mainland by Hawaiian Jew April 3, 2004

mainlanders 

Mainlanders, a term used in Newfoundland to describe people from mainland Canada (Places other than Newfoundland and PEI).

Mainlanders often isult Newfoundlanders because of their lack of understanding of Newfoundland culture or just ignorance in general. Some view mainlanders as lazy and opinionated due to the fact that Newfoundlanders usually do most of the work (i.e the Alberta tar sands)
"God damn mainlanders..."
mainlanders by David456 May 29, 2007