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1) How to describe the action you take when you had way too many drinks the night before and don't want to go to work/school.
Holyfuckingshitman, i am layup today. I think I had about 23 beers last night, but I kinda lost count after #14.
layup by pizzozo October 28, 2004
When its getting towards closing time, and everyone's cocked, you look over to the other side of the bar and that girl thats drooling drunk... yeah, she's a layup. At this point, she'll go home with anyone with a pulse. No extra effort needed, easy layup.
Mike: its gettin late man
Steve: You're hopeless Mike, at this point, layup's your only option.
Mike: Yeah, i need a layup and i need one yesterday. oh thank god, theres Welma! She'll do.
Layup by squints6969 November 8, 2011
A word for when you are faced with a certain predicament that must be worked around-- more specifically, a situation that is part impasse, part dilemma. It is an event or other such obstruction that prevents you from achieving a certain goal that usually must be puzzled out in some form or another. Good for situations where words like puzzle would be appropriate, but specifically the kind of puzzle to be found in Zelda games.

Not to be confused with holdup, which is a situation that by most definitions is a conundrum that cannot be solved through one's own power. Also not to be confused with laidup, which is to be incapacitated (usually through sickness or injury), though it is related.
Sorry I'm late, I had a bit of a layup on my way here: traffic was seriously backed up on 43rd, so I had to find another way 'round.
layup by tahutoa February 3, 2020
While urinating, aiming for the side of the toilet/urinal instead of the middle in attempt to avoid splatter.
A: Dude, I hate those urinals, my aim was great but I still got piss all over my pants!
B: Have you tried going for a layup?
Layup by quyattplease January 22, 2020

Layup Hoes 

the girl at the bar/club that you know you can get with but you just might keep her on ice in case you see a finer girl. like in basketball, a layup is the easiest shot, a three point buzzer beater is the hardest, layup hoes are easy.
damn man those layup hoes were trippin last night when they said they were choosy and had class, we all know we get it in once and done-ski
Layup Hoes by pseudo this April 12, 2011

layup drill 

a lopsided basketball game where one team is getting easy fastbreak layups one after another
Layup drill!!!! Who's guardin' me???
layup drill by jrus August 14, 2010