When you pour dope sauce on you it makes you dope. The first person to use dope sauce was Cee-Lo-Green. If Cee Lo didn't use dope sauce then he would just be some fat wierdo. Also Skrillex used dope sauce.
1. Completely trashed. Either high or drunk to the point where one's body cannot tolerate anymore.
2. A situation in which the individual is completely fucked beyond all belief.