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When an animal (humans included) is so horny and eager to mate, that they'll hump whoever comes along.

Some people think that only females experience this state, but male animals also have a reputation for being achingly randy.
"Great...! Just great! We forgot to neuter our cat, and now she's in heat! I can't stand the howling!"

"While in Frankfurt (appropriately), I once asked a German storekeeper for a 'heißer Hund'- literally 'a hot dog.' He burst out laughing, as 'heißer Hund' in German suggests a dog in heat." -Richard Lederer
in heat by Lorelili February 5, 2006
When a creature (most likely an amimal, but can apply to humans) is so horny, it'll hump anyhthing in sight.
Mona: OMG! Look at Jack!
Mae: What the fuck is he doing?
Jack(pulling out of the dog's ass): Ooooh, yeah! Thanks again, sparky!
Sparky: Woof!
in heat by sexie chocolate October 5, 2004
Synonym to horny, but with a more used for animals meaning. This can still be used to describe humans. When an animal is in heat, getting some becomes a priority, so it doesn't matter with who or what.
The stray and I were both clearly in heat so I did us both a favor by releasing my load into her. Hope I didn't get that poor thing pregnant . . .
In heat by Pop pop sizzle February 22, 2018
When you are feeling a “way” about something or someone….
DAMN THAT GURLS IN HEAT!!!
In Heat by boiwhatdahell March 17, 2022
Mad as hell. About to lay the smack down on some triflin' bitch.
Them's fighting words. She musta been in heat when she said that about Billy's gimp leg.
in heat by (r)evolution September 16, 2007
Phrase meaning either "bothered", "stressed out", or "completely blown away".
Man, I caught my gurl cheatin' wit some sucka. Dat bitch got me In Heat!!!!!