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The anus. Said with a strong "OOO" sound in place of the "uh" sound.
Gary's anoose is loose as a goose.

Gary's anoose has been wrecked by Rob, Sean, Jason, Chris, Vas, Josh, Scotty, and Adam.

That anoose is sugarmuffins good.
Anoose by skeetachya February 3, 2010
Related Words
The rectum; bottom portion of your ass, aka the asshole. Bastardization of 'anus'.
My anoose is having a very difficult time excreting the shit out of my colon.
anoose by AL August 13, 2003
anus + moose = anoose
Me: Hey guys !
Everyone: What ?
Me: ANOOSE !!!!! HOHHHHHHHHHHHHHHH
anoose by anoose August 4, 2007
Random Guy: i hate that "Anoose" he is just so damn annoying

Random Guy 2: yeah he is
Anoose by Betersyndrome March 1, 2020
A anus that is so rancid that one would consider hanging oneself after being exposed to it.
I was planning on returning the favor when I got a whiff of that anoose.
anoose by SwankeyDankey May 7, 2018

Anoose Moot

A chaotic fusion of emotional collapse and bodily tension caused by extreme gamer rage — especially when someone (usually named Bob) falls into a hole (both emotionally and in-game) and can’t get out. Said to swell deep within, where Bob’s suppressed grunts and frustration build until they erupt through an orifice somewhere between his anoose and the moot.

Origin:
Discovered during an online game where Bob got stuck in a hole and lashed out for several days and was still hurting.
Bob: "Pest, they’re coming from the west, PEST!" Bob shouted before falling into a hole and getting stuck. Moments later, a guttural outburst tore through the headset — his anoose moot had fully activated. Consumed by shame and frustration, Bob then attempted to team-kill as a form of emotional retaliation and damaged he had suffered.
Anoose Moot by JoseConseko May 14, 2025