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The feeling one has when one has been awake for to long on a variety of substances, primarily ecstasy, cocaine, and/or crystal meth.
Dude I took my last E pill five hours ago and now I'm just straight twackered.
Twackered by Rellik Uzi August 14, 2010
Related Words
twawk Twank twacked twack twanker twak twanking twacker twankies twatknot
TWACK v. To strike with great force using the back of the middle finger (usually the nail) after coiling it under pressure against the opposing thumb. Accomplished twackers can inflict great welts upon their victim's flesh.
That turd cutter pissed me off, so I twacked him right in the munt!

On the first twack
Pope jumped like a macaque;
On the second twack
Pope was taken aback;
On the third twack
Lost his marbles the old hack.
(A. S. Pushkin)
twack by Clittary Hilton November 19, 2007

Real Tawk 

Cum the fuck on man, real tawk.
Real Tawk by Randive July 15, 2020
Someone who is in the gray area between a crackhead and retard.
You're a fucking twack.
Stop twackin out
Twack by TheCreatorUBitch January 26, 2019

Twackerjack 

A sleep deprivated person that is spun out on meth.
Twackerjacks are easily detected by their severe body and facial contortions (see: Monkeyface).
Damn girl! You are completely twackerjacked. Go to bed.
Twackerjack by lledrovc July 25, 2007

twakstar 

A person who smokes methamphetamine everyday.

Sounds like the word "trackstar"
"Hey guys, that twakstar is smoking methamphetamine."
twakstar by OxTxTxO December 19, 2008