zefo Share definition Flag A god-like or Jesus-like creature. Walks on two legs. Can kick some ass. Has a hot girlfriend. Mostly seen in Canada. Also smokes a lot of weed. holy crap that kid is a Zefo. zefo by x assassin54 x April 15, 2009 0 0 Get merch Get the zefo mug. Buy Now — $32.95 See more merch