The douchiest way to respond to anyone you disagree with.
Obama: There are also those who claim that our reform efforts would insure illegal immigrants. This too is false - the reforms I'm proposing would not apply to those who are here illegally.

Joe Wilson: You lie!
by NightRaven September 12, 2009
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You lie? Is a short way to say "Are you lying?" or "Are you serious" Basically those. It is used when someone says something absolutely ridiculous and you think they are lying like the example below.
Bre--I'm related to Beyonce!
Jess--NO way!!
Bre--Yup! She's my half aunt!
Jess--You Lie?
Bre--Nope! It's the truth!
by Miss Crayzee May 23, 2009
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Is a valid response to the person who made a statement that is an obvious lie.
Obama: There are also those who claim that our reform efforts would insure illegal immigrants. This too is false - the reforms I'm proposing would not apply to those who are here illegally.

Joe Wilson: You lie!
by the_mad_rshn September 10, 2009
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a ratchet way to say, "you are a liar." or "you're telling lies."
also;
a phrase that is repeatedly used by my short king, lil uzi vert in the song "prices".
uncultured white girl: 6ix9ine is a WAYYYY better rapper than Lil Uzi Vert.

cultured people: Uh, you is a lie.
by acid kyra <3 June 10, 2020
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The shortest form of speaking 'truth to power' that exists. Useful for when long-winded replies are not possible and because 'dissent is the highest form of patriotism'.
Obama: Lie, lie, lie...

Joe Wilson: You lie!
by Gaspipe September 10, 2009
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A funner way of telling someone that they're a liar.
Macee: I don't like food.
Catie:Girl, yous a damn lie!
by Eitac September 17, 2009
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usually agreeing with someone's statement who is being honest or expressing guilt.
Tone:"Damn, my breath is stankin'"

Pete:"Man, you ain't never lie"
by Watson41side March 25, 2009
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