One of Homestar Runner's catch phrases, as well as his hilarious obsession.
The Cheat, I have a question about your costume. Are you supposed to be some kind of Witch's Brew?
by coolpersonyo August 27, 2003
An activity in which participants deficate in the same toilet bowl without flushing. After a large accumulation of feces, and the scent becomes unbearable, you have achieved a witches brew. Originated at valley stream north.
John: Yo Nik I just took a shit.
Nik: Don’t flush that we’re gonna start an ill witches brew.
by John Tartamella June 24, 2018
When one goes for a long period of time without ejaculating. The cum is brewing and festering waiting to be unleashed. Its as if a group of witches are brewing something in the bottom of a guys balls.
I'm cooking up a mean witches brew. I unleashed the witches brew all over this girl last night.
by Poundtown17 February 15, 2010
The cloudy substance created after somebody drinks a glass of milk and then proceeds to Fill the glass with water without washing it out
That weird mf charles drinks witches brew on the daily
by Sudanese charles March 23, 2021
Referring to a situation when a gentleman has not ejaculated for a long period of time. His baby batter has been brewing and thus is quite pungent and foul to the taste.
Dude, I have been stewing this witches brew for almost a month in anticipation of blowing it all over that whores face.

I busted a five roper of witches brew on that bitch and she almost vomited from the necrotic odor.
by Glass House October 26, 2011
The term used for when one throws up a little in their mouth, swallows it, then has to deal with the horrible after-taste.
Dude, after I ate that burrito and shotguned that Milwaukee's Best, I got the worst witches brew.
by BobbieSuee May 29, 2009
orginally coined by Homestar Runner, and used in mostly non sensical situations, no one is absolutely positive on the actual meaning of the term, although it has led to some speculation. Providence College scholars have listed as either
1. Alchohalic beverage
2. Female ejaculate
1. hey man, pass the witches brew
or
we are on our way to pick up some witches brew at the witch hut
2. Man, she got her witches brew all over the bed.
by James L January 21, 2005