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One of the primary languages spoken in Ghana (usually by the Akan).
Hey, I heard that Ghanaian guy speaking in Twi.
by sazzlefrazzle May 02, 2005
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Totally Wit It

to be willing to participate in something
You and yo girl wanna have a three way over at my crib? I'm totally wit it.
by Street's Disciple November 13, 2004
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Texting While Intoxicated. A newer version of drunk dialing. TWI is the phenomenon that happens when your inhibitions are lowered by the use of alcohol and you boldly send a text to someone who, if sober, you otherwise would not have.
You receive a text past midnight from an ex that says, "You are still the hottest person I know." Your current partner reads it and says, "Well your ex just got another TWI."
by iamyou March 31, 2009
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She walked by asking me “Are you Nas?”
“Why?”
“If you was I’d be so T.W.I”
“What’s that?”
Totally With It. T.W.I”
by NoNamer May 24, 2008
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twister while inebriated, othewise known as the act of playing twister under the influence of alcohol.
Hey dude, lets T.W.I tongight!
by Lisa and Amy October 26, 2006
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Internet shorthand for "that's what I'm saying."

Meaning the person wholeheartedly agrees with the concept of the previous statement.

see that's what I'm saying
> He's gotten heavy.
> He needs to get his ass to the gym.
> twis!
by tojified July 14, 2009
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