The foremost excuse in the frequent case when something that is supposed to happen doesn't; notably, when a person who promises you something doesn't fulfill the promise. The absence of a key component or ingredient is an unarguable reason why you didn't get what you wanted.

Like all excuses, There Isn't Any is a true statement (although you can't prove a negative, you can search the cupboard or the stockroom and see that There Isn't Any, if you want to be a dick) which evades all discussion of why There Isn't Any; above all, why no one did his job and planned ahead so that there might be some.
Boss: Why didn't anyone make coffee?

Employee: There isn't any.
by no_clue97 August 3, 2018
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