tweakaboss Share definition Flag An endearing term for a vagrant, bum or hobo. The kinda fella to buy minors illicit substances or always offer a ciggy. “Ayyyeeee tweakaboss!” “Can you buy us booze tweakaboss?” tweakaboss by ChrisChicken158 June 14, 2024 0 0 Get merch Get the tweakaboss mug. Buy Now — $32.95 See more merch