The effect of consuming a combination of alcohol and at least one other substance (most commonly marijuana, although prescription pain medication may be used as a substitute if you have exhausted your weed supply) Common symptoms that you are twasted are slurred speech, heightened emotional state, repeatedly stating in a high pitched voice that you are "Twasted!". No future recollection of the event. Embarrassing photos soon follow.

Ooh big daddy I'm so twasted right now.

Twasted by BadBunnyBK February 7, 2010

Twasted

The process of getting completely and totaly wasted. Usually to the point where you either A) black out, dont remember, end up with two rico suaves in your dads car, pass out still in your boots, lose your car, purse, mind, etc.

Lets get twasted and take advantage of ourselves.

Twasted by J. Field February 14, 2006

Twasted

The level of intoxication experienced after drinking and smoking that sticky stanky.

I shouldn't have taken that last hit, the herb and vodka got me all sorts of twasted!

Twasted by ShimmyVB August 26, 2015

Twasted

It's the stage after tipsy before wasted

Nya, lexi, nicole and Lisa were all twasted at the Kearny party!! 44 Clinton Ave be there!!!

Twasted by Let's get lit July 26, 2017

Twasted

To be strange, weird, spasticated, or well done in.

You're well twasted, you are.

Twasted by Dommo September 21, 2005