1 definition by BadBunnyBK

The effect of consuming a combination of alcohol and at least one other substance (most commonly marijuana, although prescription pain medication may be used as a substitute if you have exhausted your weed supply) Common symptoms that you are twasted are slurred speech, heightened emotional state, repeatedly stating in a high pitched voice that you are "Twasted!". No future recollection of the event. Embarrassing photos soon follow.
Ooh big daddy I'm so twasted right now.
by BadBunnyBK February 7, 2010
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