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Trisomy 21

Trisomy 21 is a condition that occurs during meiosis in sex cell division. This means the production of egg and sperm cells. This condition is when cells do not reproduce properly, also called nondisjunction. This causes one gamete to have 2 #21 chromosomes. When this is combined with the opposite gamete, it causes there to be 3 #21 chromosomes. In a "regular" human,m there are 46 chromosomes overall. In a person with Trisomy 21, there are 47.

This is what happens for persons who have what is diagnosed as "down syndrome". It is because the person has too MUCH genetic information.

Some of the symptoms of Down Syndrome, or Trisomy 21 are:
-mental retardation
-wide range of mental abilities
-round, full face
-enlarged and creased tongue
Example 1:

Joe: "Did you hear about the new kid? He has down syndrome! Poor guy!"
Bob: "We learnt about that in Bio class!"

Example 2:
Joe: "Your mama is sooo fat..."
Bob: "Oh ya?! Well, you have Trisomy 21!"
Joe: *silence*
Trisomy 21 by light=2.997924562 November 21, 2011

trisomy 21

a quintet rock group based out of southington ct,they willl rawk your sawks off
www.trisony21.tk r00lZ!!!
trisomy 21 by gabe October 23, 2003

Down Syndrome "Trisomy 21" 

I'm really surprised at the illiteracy of our society. I think that many people have a learning disability, especially when you ask them what they think Down Syndrome is. It's actually called Trisomy 21. People with this CONDITION (not disease) have an extra chromosome. The 21st chromosome tripled at conception. Most down syndrome people have medical problems such as, heart defects, liver problems and kidney problems. Their weight problems come from their thyroid being too high or too low. These guys can learn, just a little slower than you and I. This is not a disease, it is a condition. They also have features that aren't like ours, which makes them unique. Their not perfect, but neither are we. When you find someone who is, then I think you'd better call the American Medical Association. What makes them much different than some of you that have tried to define this condition is that they are better than you because they have no concept of judgement. You will never hear them judge someone elses way of life. I've read many of the definitions on this site and I can only say that I'm really dissapointed to know that their are that many cruel people out there. YOU rude people are the reason that down syndrome people are rude. They have to protect themselves from people like you. What "DISEASE" do you have that makes you the way you are? These kids are blessed children of God. They don't know what evil is. In closing, the next time you want to create your own definition of something, use your brain and look it up in a dictionary first. As for those of you who bashed this condition, you just made yourself look like a real dumb-ass.
I am a mother of a beautiful little girl who has down syndrome. I can only say to you who down this conditon that you are the ones with a very selfish disease called "JUDGEMENT"
A small piece of information. Derived from the word ken, used often in the scottish language and is synonymous with knowledge.
Person 1: "Hey I don't get this shit. How do you solve this problem?"
Person 2: "I got that one. Give me some kenlets on this assignment and I'll help you w/ that one."
kenlet by Norma Y. October 8, 2005
Word of the Day on July 13, 2026

I mean I guess bro

a word of expression to when you give up on comprehending someone's words of ignorance, stupidity, absurdity or are too exhausted to formulate a proper response.

Commonly seen in TikTok comment sections in replies to lazy attempts at humor, overconfidentally incorrect statement, or an over-the-top comment or when someone completely misses the mark on something.
"actually... incorrect statement, hope this helps!"
"I mean I guess bro"
Word of the Day on July 12, 2026

abandonware 

n. software that is no longer sold or supported by the original publisher / developer, often found as free downloads on the internet because it cannot be obtained elsewhere. Not legal, but often seen as morally acceptable because the company that made it is no longer selling the title, nor releasing it as freeware, therefore abandonware is "keeping the game alive", so to speak.
Doom II is not abandonware because id still sells it, while The Incredible Machine is not sold, therefore is abandonware.
abandonware by Spoom October 24, 2003
Word of the Day on July 11, 2026