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take a powder 

Stop bothering me and/or relax yourself, specifically by taking a break in the powder room. There you can put some talcum on your face to cool off. See go take a swim and fly a kite. Old fashioned.
Richie: "I only meant it playfully."
Doanh: "WHATEVERR"
Richie: "Go take a powder!"
take a powder by milwaukeetalkie January 1, 2009

take a powder 

Chill out...relax...calm down. As in "Go powder your nose or something (for a guy, too) and CALM THE FUCK DOWN"
"Dude, WTF?! Are you on the rag or something? We were TOTALLY kidding. Go take a powder and your beer'll be here when you get back"
take a powder by popokus September 7, 2011

take a powder 

Mary: did you hear? johnny decided to take a powder yesterday.
Jake: When's his funeral?

take a powder 

Uhhh sorry, where is your bathroom? I need to take a powder...
take a powder by Rohou August 19, 2008

Take a powder 

To snort cocaine

Get hit with a wave of snow
“Yo bro take a powder. We’re goin to the edm stage”

When your bro is shredding hard on the slopes and slaps you with a big wave of snow and says “take a powder”

take a powder 

Polite way of saying you need to fart or leave abruptly. back in the days of newspaper funny pages or cartoons farting was commonly depicted using a poof of body powder to show they farted. this was only known by kids or hip people so when you said it adults wouldent get it.
Well if you excuse me i need to go "take a powder" jonny said as he abruptly left the diner table to great amuse.
take a powder by looneyalykey August 26, 2025