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Substance D 

1. Substance D is a fictional addictive amphetamine-like psychoactive drug, also known as "Slow Death", "Death" and "D", that is depicted in Philip K. Dick's novel "A Scanner Darkly". It's derived from the fictional flower "Mors ontologica".

2. By extension, Substance D can refer to amphetamine (speed).
"What he sold me as 'candy' actually turned out to be 'Substance D'."

This is a more subtle way to refer to amphetamine in a conversation if you don't want to attract too much attention.
Substance D by Electric Sheep March 15, 2009
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Substance abuse disorder 

New clinical/medical term for a person's drug abuse issues
Substance abuse disorder should be abbreviated as sad, where sad is a noun. I don't suffer from sad.

Normally occurs at the tail-end of an upset-stomach deuce. When you fire off a bunch of quick-hitting farts, in a firecracker pattern, with no substance or stink with the sound being amplified by the toilet bowl. 

Normally occurs at the tail-end of an upset-stomach deuce. When you fire off a bunch of quick-hitting farts, in a firecracker pattern, with no substance or stink with the sound being amplified by the toilet bowl. which is a good messgae

Suga-Drug Substance 

Yo, my homie, get me some of dat Suga-Drug Substance!

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<.7.9.7.6.><.7.9.7.6.><.7.9.7.6.> Despite his parents wanting him to be an athelete. after years of substance abuse and many failed rehabilitations, Sparta continued to fight for Fucks Off Sake On Individuals<.7.9.7.6.><.7.9.7.6.><.7.9.7.6.>
<.7.9.7.6.><.7.9.7.6.><.7.9.7.6.> Despite his parents wanting him to be an athelete. after years of substance abuse and many failed rehabilitations, Sparta continued to fight for Fucks Off Sake On Individuals<.7.9.7.6.><.7.9.7.6.><.7.9.7.6.>

Substance Toddler 

(n.) A person who can only tolerate a small amount of drugs, alcohol, etc.
(n.) A lightweight
Jimmy: Where's Carl?
Ron: He passed out after like 3 beers, man.
Jimmy: What a substance toddler!
Substance Toddler by Ankylosaurus February 21, 2010

Whore Substance 

When a woman in the age gap, 24 - 46 snorts cocaine (or other snortable illicit substances, including sherbet) through a a straw inserted into her vagina hole. This procedure must tke place, in humid conditions, between the times, 2:45am and 3:32am.
The time is 2:99 in this humid enviroment, and their is whore substance in my front bum.
Whore Substance by whore humper January 6, 2011