Referring to the City of San Francisco. Usually used by Inland or Southern Californians or other non-Bay Area natives. Most Bay-Area residents refer to San Francisco simply as "the City".
Tourist: Let's go to San Fran!

Bay Area Resident: You mean, the City.

Tourist: Right.....
by NorCal_Ryan October 29, 2006
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The most annoying way possible to refer to the City of San Francisco. Even more annoying than calling it Frisco. Frisco is actually endearing by comparison.
Duh, I'm going to San Fran. Duh-har har.

(Gets punched in the face).
by doughnuts October 10, 2011
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That feeling you get when the fog is rushing into the City, the bay is blue and all the hodgepodge of the City's population is out and about. No judgments, no intolerance.
Walking to the Ferry Building gave me a total San Fran zen.
by eurekadouglass June 09, 2006
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A gay act where 2 penises intertwine.
Carlos: Ohh ya, that gay sex is great! Oh shit we just San Fran dookued our penises.

Steve: I actually kinda like it
by Carlossmith98420 May 28, 2020
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a bloodly or glazed bowl movment resulting from rough anal intercourse.
lance:i passed out in san fransisco and my ass really hurts.
Carl: just wait till u have the san fran shit.
by RED I August 18, 2006
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