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An Italian surname, taking its origins from the 'Pugliatti 'of the Puglia region of Southern Italy. A common surname in Sicily (rank 5th) and Northern Italy due to south-north migration. Not to be confused with Pugliese an adjective describing the people of the Puglia region of Italy.

Come vai di cognome? (what's your surname?) = Puglisi
puglisi by dan puglisi September 4, 2008
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moody, inconsiderate, acts like or is first born
"I want to go to mighty taco" ~puglisi "we dont"~4 other people "its my house and my tv and my halo so we're going to mighty"~puglisi
puglisi by BEAT MODE March 9, 2005
One who lacks the maturity to interact with his peers, and henceforth occupies his time with middle-school and high-school girls.

See: pedophile
Has anyone ever been a puglisi?
puglisi by anonymouswhat May 14, 2006

jade puglisi 

a anti christ who will bring upon the end of days
jade puglisi by thepotato64 October 17, 2017

jade puglisi 

evil the devil a lying person who is filled with great evil also known as the anti christ wo will bring upon the end of days
jade puglisi by thepotato64 October 17, 2017
The Lebron James of football
Pulisic is the lebron James of football
Pulisic by Makengo.com March 25, 2022
The GOAT
Did you see pulisic play today?
Yeah he came on for about 30 minutes and already got a hat trick
Pulisic by ow6415 November 5, 2020