A Potent strain of marijuana that originated in NYC. It it often made by lacing weed with Morphine to create a stronger and longer lasting high.
"I got that Piff if your looking for something strong"

by Smith33 March 4, 2009
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Girls can Queef and when the air is locked within the penis and released to make a whistle its a PIFF.
Holy shit what the fuck was that? is someone watching us? no i just piffed thats all. no one is whistling
by A-oogen February 4, 2010
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Singer and guitarist from West Orange, Nj. Leader of the Modern Day Hippie Movement.
by Chad Piff March 13, 2017
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The best bud you can get from your dealer
bangin shit
Da piff nigga
by black artie September 22, 2010
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