1.To be screwed,f**ked, or otherwise incapacitated.

2.A way to describe a bad situation.
1.Man he's oofed.

2.Damn, that test was oofed man.
by S@m P November 11, 2004
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when you die in roblox but u fall in love with a new sound
bro stop saying that crap oof oof oof oof oof oof oof oof oof oof
by Asianguythatushouldnotbeseeing December 18, 2018
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when you don't really care but should say atleast something
You- "I think I'm having a heart attack"
Me- "oof"
by mikaschm March 22, 2018
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You did not know what to write, so you just typed in "oof".
by metrost February 9, 2018
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Originating from the death sound effect of an online game known as Roblox, "oof" is a common expression or response shared when one is faced with a melodramatic defeat or taken an embarrassing L in any real-world situation.

The sound effect from the game is sampled in many online videos, sounding like a small child who has been kicked in the stomach. Humor can be found in the unwavering consistency of the "oof" sound effect, as well as the obvious trauma endured by the child-- undoubtedly an odd choice for developers to include in a children's game.
Guy 1: Bro, I called Susan like 50 times last night, and when she finally answered she told me to go kill myself.

Guy 2: Oof
by 🐺 November 11, 2018
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