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Being under the influence of energy enhancing drugs. e.g. ectasy, and speed
Awww man, last nite I was so off it, it was unreal.
off it by Chaotic*Toffee May 12, 2006
Im pretty off work aye.

Your such a gay cunt, off you.

"I heard someone ripped ya plants man" Yeah, I was pretty off it.
off it by biz to tha nizzle June 20, 2006
lets off it/ off it go away
Off it by user3030 May 24, 2022

Off it's tits 

Something that is really good. Can also be used to describe someone who is drunk or is "off their tits".
That pizza we had last night was off it's tits!

Gary was so drunk last night, he was off his tits!
Off it's tits by Mr Reston January 16, 2010

come off it 

A very Cockney (East-London Slang) phrase, used to express rejection or disbelief. It can also used in a friendly way.
come off it by NoStringsOnJay March 25, 2016

Break the chain off it

Having sex with a milf or cougar who has kept that pussy behind rusty gates for a while -- metaphorically speaking. If the milf or cougar in question has literally kept the pussy behind rusty gates, you do not want to break the chain off it.
Stevie Nicks? You know it's been a while, but I'd definitely break the chain off it.