ms. six o'clock Share definition Flag straight- laced white woman. flat ass white woman. straight up and down like the hands on a clock at six. "Don't bother. She's Ms. six o'clock and she doesn't do the nasty with the Brothas. ms. six o'clock by Bape747 November 11, 2009 0 0 Get merch Get the ms. six o'clock mug. Buy Now — $32.95 See more merch