meat on a bun Share definition Flag Any form of meat placed between bread or buns that when eaten, results in intestinal distress. A few hours later, yeah, I got the runs. I knew right away, It was meat on a bun. meat on a bun by edley March 3, 2007 0 0 Get merch Get the meat on a bun mug. Buy Now — $32.95 See more merch