Man Disease 

The affliction of not seeing something even when it is right in front of your face.

When a man looks in the pantry and cannot find the replacement mayonaise, he has man disease.

Man Disease by marshalynn January 11, 2011

Man Disease 

Were either you are looking at something but do not see it or you always have to be right.

"Honey, does anything look any different?"

"Um...no?"

"Seriously! Typical man disease."

Man Disease by Captain DRock April 25, 2010

Old Man Disease 

An abnormal, chronic condition that utterly destroys the spirit of those unfortunate enough to be affected. Victims usually enter an initial phase of existential shock coupled with long bouts of heavy, heavy introspection. Symptoms usually include a decreased will to participate in all social activities, as well as a general lethargic and depressing outlook. This disease is highly infectious and may be transferred merely by word of mouth in fortuitous circumstances. This disease carries no race bias.

Treatment: Direct intervention by loved ones, making significant amounts of money, getting laid.

H: Sup Jones?
J: Oh, hey Haboob.
H: How's it goin?
J: Oh, dude.. I'm super stressed about all this reading I got to get done this week. Plus my arms are super sore from cleaning all those big ass boats all day. I don't even know what I'm doing with my life anymore(patient undergoes period of existential shock).
H: I was not expecting that kind of real shit. So... I guess that means you're not coming out tonight?
J: Nah man, I gotta get my shit together. I'll have like a beer or two... maybe. Hey, maybe you should start thinking about taking school seriously too.
H: ....

1 week later...

L: Sup Haboob?
H: Oh, hey Laz.... How's it goin?
L: Oh life's great man, I got this new job and I'm making good money. Hours are shit but its good. How's yours?
H: Aw, man. I've been studying all week and feel like shit. I feel like I'm getting too old for all this partying (patient undergoes period of existential shock). I gotta make money man, 20 is the new 55. I've been trading bitcoins all week.
L: Oh, shit. Does that mean you're not coming out tonight?
H: I'll come around, maybe have one beer.
L:....

2 weeks later....

P: Yo, Laz! Let's get hanned tonight~
L: Can't man. I'm allergic to beer.
P: Man, this dumbass nigga got the Old Man Disease.

Old Man Disease by koolgraps December 4, 2013

Bush-man disease 

This is what happens when you know someone that is trying to find out if your home for all the wrong reasons. You camo up and hide out in the bushes waiting for them to come over so you can introduce them to Me. Gauce

Billy Bob kept calling me to see if I was home, after his fith call I developed bush-man disease.

Bush-man disease by Dirty Dick Dale October 16, 2018

Spider-Man Disease 

Spider-Man Disease is a disease in which someone has hallucinations where they believe that they are something more than human, often believing that they have superpowers. It is named after the famous superhero that people later figured out was hallucinating.

“Why's he kicking the air"
“Oh don't worry he just has Spider-Man Disease"

Spider-Man Disease by The Kash Register October 25, 2022

Little Man's Disease 

It is a condition where a small or short man will be generally more agressive towards tall or larger men.

The person with Little Man's Disease is trying to make himself seem stronger or better than the bigger person and is generally hostile or moody towards them.

'That geezer over there must have little man's disease. Look at him trying to start a fight with them to massive guys'.

Little Man's Disease by Oliver Vantini September 29, 2008

Little Man’s Disease 

Little Man’s Disease: A disease of short males marked by aggressive antisocial behavior and constant overcompensation resulting in pompous mannerisms such as spitting, twitching, swearing, speaking loudly and tough talk.
The disease only affects teenagers or men who are less than 5’ 6” tall. The severity of this disease is inversely proportional to the height of the sufferer. Other characteristics of this scourge are a very short penis, acne, low I.Q and bad etiquette. The poor bastards usually drive jacked up pick-up trucks lacking mufflers. Often these males are homophobic to the point of insanity because of latent sexual orientation issues.

You must have Little Man’s Disease.
He is such a worthless asshole he must have Little Man's Disease.
Little Man's Disease is an untreatable epidemic in this country.
Some of my best friends have Little Man’s Disease.

Little Man’s Disease by Dr. Vinnie Boombaa May 4, 2007